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Let's
Talk
About
Disease.
Disease
can have
either
hereditary
or
environmental
causes
or both,
and can
be
inherited
on
either
recessive
or
dominant
genes,
or due
to a
predisposition
with
variable
causes
including
dietary
deficiencies
or
imbalance,
stress,
administration
of
certain
drugs,
or
anything
which
compromises
the
immune
system
of the
individual
dog such
as over
vaccination
or the
feeding
of -
Unwholesome
Commercial
Dog
Foods.
See
Links
Page
Diseases
Inherited
Via
Dominant
Genes
Diseases
transmitted
through
dominant
genes
can be
relatively
simple
to breed
out of a
particular
line of
dogs by
either
terminating
the
bloodline
from
whence
it has
come or
by
judicious
breeding
practices.
An
example
is the
eye
disease
prcd-PRA.
This
disease
can be
idendified
via a
DNA test
which
became
available
in 2007.
Dogs are
classified
as
either
'Clear'
'Carriers'
or
'Affected'.
By
DNA
testing
progeny
prior to
retaining
breeding
stock
and
keeping
only
'Clear'
dogs for
further
breeding
this
disease
can be
stamped
out of
that
bloodline
in one
generation.
There is
a modern
trend
for
breeders
to test
for a
number
of
diseases
in their
breeding
stock
and it
can look
very
impressive
to see a
list of
health
testing
results
displayed
as some
kind of
badge of
honour
which
places
them
above
the rank
and
file.
In
principle
this is
impressive.
In
reality
it is
pointless
to test
for a
dominant
gene
disease
which
has
already
been
eliminated
from
that
breeding
line
unless
there is
a loose
cannon
by way
of a new
unknown
bloodline
which
has been
used
with it
in the
breeding
program.
Let's
clarify
this.
Let us
suppose
that a
dog
tested
'clear'
for prcd-PRA
is mated
with
another
also
tested
'Clear'.
Because
it is
impossible
for any
of the
offspring
to be
anything
other
than
'Clear'
it would
be
pointless
testing
that
offspring.
But it
would
look
impressive
(to the
uninitiated)
added to
the
health
testing
list!
Diseases
Transmitted
Via
Recessive
Genes
Not so
easy are
the
diseases
transmitted
through
Recessive
genes.
These
tricky
little
genes
can skip
a number
of
generations
and be
'silently'
carried
through
dogs
which
are
themselves
perfectly
healthy
and who
show no
clinical
or
symptomatic
signs of
the very
disease
they are
'carrying'.
An
example
of a
recessively
carried
disease
is Hip
Dysplasia
(HD).
Progeny
of
several
generations
of
parents
with
excellent
hips on
both
sides
can
still
produce
dysplastic
offspring
without
warning.
Conversely
certain
individuals
with
poor
graded
hips can
produce
offspring
with
excellent
hips!
This
disease's
very
unpredictability
makes it
necessary
to test
every
successive
set of
parents
before
they are
bred.
It is no
guarantee
of
producing
good
hipped
dogs but
it is
the best
a
breeder
can do.
Inherited
Canine
Disease
Can Be
Breed
Selective
This
means
that
particular
breeds
are
prone to
develop
their
own sets
of
inherited
diseases
and the
list of
possible
canine
diseases
is
overwhelming.
Tests
are
available
for
some,
but many
others
can only
be
identified
post
humorously.
Some
occur at
a young
age and
others
are
mature
onset.
List of
Inherited
Diseases
Shared
by the
Labrador
and the
Poodle
DISEASE
|
LAB |
POODLE |
|
ADULT ONSET GROWTH HORMONE DEFICIENCY |
|
Y
|
|
ATOPIC DERMATITIS |
|
Y |
|
ATYPICAL PANNUS |
|
Y |
|
BLOAT |
|
Y |
|
DILUE COLOR ALOPECIA HYPOTHYRODISM |
|
Y |
|
DISTICHIASIS |
Y |
Y |
|
ENTROPION |
Y |
Y |
|
EPILEPSY |
Y |
Y |
|
EPIPHORA |
|
Y
|
|
FACTOR V111 OR AHF DEFICIENCY |
Y |
Y |
|
HEMOPHILIA A |
Y |
Y |
|
HIP DYSPLASIA |
Y |
Y |
|
IRIS ATROPHY |
|
Y |
|
JUVENILE CATARACT |
|
Y |
|
LACRIMAL DUCT ARTRESIA |
|
Y |
|
MICROPHTHALMIA |
|
Y |
|
OSTEOGENESIS IMPERFECTA |
|
Y |
|
PATENT DUCTUS ARTERIOSUS |
|
Y |
|
PROGRESSIVE RETINAL STROPHY |
Y |
Y |
|
RENAL DYSPLASIA |
Y |
Y |
|
RETINAL DETACHMENT |
|
Y |
|
SEBACEOUS ADENITIS |
|
Y |
|
VON WILLEBRANDS DISEASE |
|
Y |
|
BILATERAL CATARACT |
Y
|
|
|
CYSTINURIA |
Y |
|
|
CARPAL SUBLUXATION |
Y |
|
|
CRANIOMANDIBULAR OSTEOPATHY |
Y |
|
|
DWARFISM ASSOCIATED WITH RETINAL DYSPLASIA |
Y |
|
|
DEFICIENCY OF TYPE 11 MUSCLE FIBERS |
Y |
|
|
SHOULDER DYSPLASIA |
Y
|
|
|
HYPOGLYCEMIA |
Y |
|
|
HYPOTHYROIDISM |
Y |
|
|
HYPERTROPHIC OSTEODYSTROPHY |
Y |
|
|
DIABETES |
Y |
|
|
MISSING TEETH |
Y |
|
|
PROLAPSED RECTUM |
Y |
|
|
MELANOMA |
Y |
|
|
PROLAPSED UTERUS |
Y |
|
|
CONGENITAL PHIMOSIS AND CUTANEOUS
MAST CELL TUMORS |
Y |
|
|
COLOBOMA |
Y |
|
|
CONGENITAL HYPOTRICHOSIS |
Y |
|
|
MEGAESOPHAGUS |
Y |
|
|
FOOD ALLERGY |
Y |
|
|
LEUKOTRICHIA |
Y |
|
|
VITAMIN A RESPONSIVE DERMATITIS |
Y |
|
|
PERSISTANT PUPILLARY MEMBRANE |
Y |
|
|
DISEASE |
LAB |
POODLE |
|
COPPER TOXICOSIS |
Y
|
|
|
FACTOR 1X DEFICIENCY |
Y |
|
|
ELBOW OSTEOCHONDROSIS |
Y |
|
|
MUSCULAR DYSTROPHY |
Y |
|
|
RECEPTOR DYSTROPHY |
Y |
|
|
UNUNITED ANCONEAL PROCESS |
Y |
|
|
HEREDITRAY MYOPATHY |
Y |
|
|
ATHEROSCLEROSIS |
Y |
|
|
|
|
|
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Even if
all
these
diseases
were
able to
be
tested
for the
sad
truth
remains
that if
breeding
stock
were
tested
for each
and
every
one, the
price of
a puppy
would
escalate
to such
highs
that
only the
very
wealthy
would be
able to
afford
one.
The best
that any
breeder
can do
is to
test for
any
disease
which is
known to
be
present
in their
own
breeding
lines,
and to
either
cull
those
lines
altogether
or
continue
testing
every
parent
and
every
puppy
before
sale,
and as
many of
these
diseases
are
mature
onset
with no
process
as yet
in place
to test
for
predisposition,
it would
no
longer
be
possible
for
anyone
to adopt
a puppy,
but only
adults
which
the
breeder
has kept
for
testing
up to
two and
three
years of
age.
It is
'fashionable'
to lay
blame at
the
breeder's
door if
a puppy
grows up
to
develop
a
disease,
but in
reality
every
conscientious
breeder
is
devastated
to hear
of any
of their
stock
becoming
ill
despite
their
best
efforts.
Nevertheless
breeders
of
integrity
still
offer
generous
health
warranties
on the
puppies
they
breed
and most
work
hard at
keeping
abreast
of new
technologies
which
become
available
regarding
testing,
treatments
and
preventions.
An
owner's
responsibility
is to
themselves
keep
abreast
of
breaking
news
regarding
the
advisability
or
otherwise
of
feeding
commercial
dog
foods,
for over
vaccinating
and in
questioning
their
vet when
certain
drugs
are used
to treat
health
problems
that may
occur
over
time.
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